Stenting for Severe C7 Stenosis of Internal Carotid Artery (ICA) and Related Literature Review

Case Report

Austin Surg Case Rep. 2023; 8(2): 1060.

Stenting for Severe C7 Stenosis of Internal Carotid Artery (ICA) and Related Literature Review

Xiao-Dong Wang1; Jian-Ping Zhang1,2; Jin-Gang Bao1,2; Xin-Wei Zhu1,2; Ri-Le Wu1,2*

¹Inner Mongolia Neuroscience Society, Hohhot, China

²Department of Cerebrovascular, Inner Mongolia Hospital, Hohhot, China

*Corresponding author: Ri-Le Wu Department of Cerebrovascular, Inner Mongolia Hospital, Hohhot, China. Email:wurile@hotmail.com

Received: September 13, 2023 Accepted: October 09, 2023 Published: October 16, 2023

Abstract

Intracranial Atherosclerosis (ICAS) is a common cerebrovascular lesion worldwide and an important cause of stroke [1]. Non-modifiable risk factors include age, gender, and genetics, with age being a key factor and atherosclerosis usually progressive, with no clinical manifestations until middle age. Ischemic Heart Disease (IHD) has increased fivefold among people aged 40 to 60. Before menopause, women are less prone to atherosclerosis than men, and the incidence of atherosclerosis is increased in postmenopausal women [2,3]. The inheritance of various genetic polymorphisms and the accumulation of family risk factors (such as diabetes and hypertension) create multiple conditions for the formation of atherosclerosis [4]. On the other hand, modifiable risk factors, such as smoking, hyperlipidemia, diabetes, and high blood pressure, can be improved by adjusting daily life. Studies have analyzed that white people are prone to extracranial arterial occlusive disease, while Asian, black and Hispanic people have a higher risk of intracranial atherosclerotic disease [1]. Therefore, the prevention of atherosclerotic disease, has been very urgent, to increase publicity, from the source to solve the problem.

Introduction

Inner Mongolia Autonomous Region Hospital is located in Hohhot, China. The cerebrovascular department is the key department of the hospital, which undertakes the heavy task of the prevention and treatment of cerebrovascular diseases in the western cities of the Inner Mongolia Autonomous Region, and also undertakes the scientific research tasks of the Inner Mongolia Neuroscience Society. Atherosclerotic diseases, especially vascular diseases of the nervous system, have a high incidence in the northern region. This is just one of the cases we've treated. Share and promote communication.

Case Presentation

A 70-year-old male patient experienced sudden left limb weakness with progressive aggravation and dizziness 10 days ago. He was admitted to our hospital on August 29, and CTA indicated (Figure 1:1) Aortic arch atherosclerosis 2) Non-calcified plaque in the distal segment of the Left Common Carotid Artery (LCCA) with mild luminal stenosis 3) Mixed and non-calcified plaque in the segment at the beginning of the Internal Carotid Artery (ICA) with bilateral common carotid artery bifurcation and mild luminal stenosis 4)Multiple calcification and mixed plaque in C2-6 segments of bilateral internal carotid arteries with mild to moderate stenosis 5) Small localized protrusions at segments C4 and 6 of the left internal carotid artery, excluding aneurysms; The M1 segment of the right middle cerebral artery was not developed, and occlusion was considered. 9) Limited lumen stenosis of the right anterior cerebral artery. Hypertension for more than 10 years. No diabetes, coronary heart disease. Neurological examination found muscle strength level IV in the left limb.Aspirin, clopidogrel bisulfate tablets, atorvastatin calcium tablets were given for antiplatelet and lipid-regulating plaque stabilization. On August 30, the patient was told to control diet and rest well after 10 PM. The nurse prepared the skin in the groin area and changed the operating clothes. The doctor ordered heparin sodium injection, uradil injection, lidocaine, dexamethasone and diphenhydramine.Cerebral arteriography was performed on August 31. The surgical procedures were as follows: supine position, routine disinfection and laydown of the right groin area, right femoral artery puncture after local anesthesia, insertion of 5F arterial sheath, 5F single bend angiography catheter guided by 0.035 wire, and left and right carotid artery and left and right vertebral artery angiography were performed respectively. The results suggested (Figue2) that the right middle cerebral artery was occluded, the right internal carotid artery C7 segment was severely narrowed, the right vertebral artery compensated to the right brain through posterior circulation, the left carotid artery and the left vertebral artery were well developed, and no abnormalities were found in the venous system. After the operation, the artery sheath was removed and pressed for 15 minutes to stop bleeding and pressure bandaging.After operation, fluid rehydration prevented the occurrence of contrast nephropathy, uradil micropump was pumped to control blood pressure, the patient's condition was stable, and surgery was scheduled.Prep for surgery on the morning of September 6th. On September 7, percutaneous carotid stent implantation under general anesthesia was performed. The procedure was recorded as follows:Stenting with severe stenosis C7 segment of the right Internal Carotid Artery (ICA) was performed under general anesthesia.Lay the surgical sheet after disinfection. The 6F arterial sheath was inserted into the right femoral artery by puncture, and the 6F guided catheter was inserted into the C3 segment of the right Internal Carotid Artery (ICA) by a multifunctional catheter guide ribbon, and the Y-valve and three-way catheter were connected. The right internal carotid artery (ICA) angiography was performed by continuous pressure infusion of heparin saline. 3,000 units of heparin intravenously. The guide wire (SYNCHR-14 300mm )was sent to the A2 segment of the right Anterior Cerebral Artery (ACA), and the balloon (Gateway 3.5mm×9mm 8atm) was expanded at the stenosis, and the balloon was withdrawn, and the stenosis was significantly improved by angiography. The microcatheter (Excelsior XT-27 150cm×6cm) was sent along the guide wire (SYNCHR-14 300mm) to the right anterior cerebral artery at a distance of A3, the microcatheter was withdrawn, and the stent system (Neuroform-EZ 4.5mm×20mm) was placed along the microcatheter at the stenosis. Release the support when the location is correct. Reimaging showed sufficient stent expansion (Figue4). Intracranial angiography showed significant improvement in intracranial blood supply. The artery sheath was pulled out and the femoral artery was closed by the closure device. The patient was awake and answering questions correctly after surgery, but there was poor movement of the left limb. Intracranial thrombosis was considered. In order to confirm the diagnosis again, cerebral arteriography was performed, left femoral artery puncture failed, right femoral artery puncture was performed again, right carotid arteriography was performed after success, and microthrombus formation was found in the bifurcation of the right pericallosal artery, and distal blood flow was patency. Tirofiban 5ml was immediately injected into the artery and observed for 10 minutes. The patient had correct answer. The muscle strength of the left upper limb was grade 4, and the muscle strength of the left lower limb was grade 3. After the patient returned to the ward from the operating room, brain CT examination showed no obvious abnormality (Figue 5), and Tirofiban was injected with 6ml/h of micropump as the initial speed and gradually adjusted. On the morning of September 8, the muscle strength of the patient's left limb returned to the level of muscle strength before admission and was gradually improving.